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Peptide record

TPDB03370

Antibacterial Antifungal Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB03370
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGAVLIVLTTGLPALISWIKRKRQQ
Physicochemical Analysis
C131H227N37O32
NDCEHMFY
IL
2832.47
12.42
4
0
13
+4
0.12
0.596
150.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
194.18
5
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
2
Q
3
G
0
H
4
I
4
L
2
K
0
M
0
F
1
P
1
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 4 L: 4 K: 2 M: 0 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
26
C131H227N37O32
2832.47
12.42
+4
0.12
0.596
Evidence Records 2 records
Evidence 1 Activity

Activity

30% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
30% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Studies on the mode of action of the antifungal hexapeptide PAF26. | Antimicrob Agents Chemother | 2006
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis