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Peptide record

TPDB03354

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB03354
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWKSFLKTFKSAKKTALHTALKAISS
Physicochemical Analysis
C137H226N36O34
RNDCEQGMPYV
K
2921.52
11.29
8
0
11
+7
2.05
-0.308
75.38
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
188.26
7
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
3
L
7
K
0
M
2
F
0
P
4
S
3
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 7 M: 0 F: 2 P: 0 S: 4 T: 3 W: 1 Y: 0 V: 0
Chemical Descriptors
26
C137H226N36O34
2921.52
11.29
+7
2.05
-0.308
Evidence Records 1 records
Evidence 1 Activity

Activity

14.3% Hemolysis
Toxicity
1000 µg/mL
Hemolytic Cytotoxic
14.3% Hemolysis | 1000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of single amino acid substitution on the biophysical properties and biological activities of an amphipathic ?-helical antibacterial peptide against Gram-negative bacteria. | Molecules | 2014