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Peptide record

TPDB03342

Antibacterial Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB03342
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KKLFKKILKYLAGPAKKLFKKILKYL
Physicochemical Analysis
C157H266N36O29
RNDCEQHMSTWV
K
3122.06
10.93
10
0
14
+10
1.90
-0.100
127.69
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
2980
95.45
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
6
L
10
K
0
M
2
F
1
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 6 K: 10 M: 0 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
26
C157H266N36O29
3122.06
10.93
+10
1.90
-0.100
Evidence Records 4 records
Evidence 1 Activity

Activity

83% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
83% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 2 Activity

Activity

93% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
93% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 3 Activity

Activity

98% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
98% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 4 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis