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Peptide record

TPDB03316

Antibacterial Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB03316
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
IARRALKKAKRAAHKIPAAKKFARR
Physicochemical Analysis
C128H230N48O26
NDCEQGMSTWYV
A
2857.54
13.01
12
0
12
+11
7.73
-0.828
78.80
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
8
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
2
I
1
L
6
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 2 L: 1 K: 6 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
25
C128H230N48O26
2857.54
13.01
+11
7.73
-0.828
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
<5% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial activity and mechanism of action of analogues derived from the antimicrobial peptide mBjAMP1 isolated from Branchiostoma japonicum. | J Antimicrob Chemother | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Antibacterial activity and mechanism of action of analogues derived from the antimicrobial peptide mBjAMP1 isolated from Branchiostoma japonicum. | J Antimicrob Chemother | 2018