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Peptide record

TPDB03312

Antibacterial Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB03312
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
IARRNLCASLRARHTIPQCKKFGRR
Physicochemical Analysis
C125H219N49O30S2
DEMWYV
R
2952.54
12.41
9
0
8
+8
5.67
-0.748
74.40
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
125
4.23
6
Residue Composition
number
3
A
6
R
1
N
0
D
2
C
0
E
1
Q
1
G
1
H
2
I
2
L
2
K
0
M
1
F
1
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 6 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 1 I: 2 L: 2 K: 2 M: 0 F: 1 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
25
C125H219N49O30S2
2952.54
12.41
+8
5.67
-0.748
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
<5% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial activity and mechanism of action of analogues derived from the antimicrobial peptide mBjAMP1 isolated from Branchiostoma japonicum. | J Antimicrob Chemother | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Antibacterial activity and mechanism of action of analogues derived from the antimicrobial peptide mBjAMP1 isolated from Branchiostoma japonicum. | J Antimicrob Chemother | 2018