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Peptide record

TPDB03273

Antibacterial Antiparasitic Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB03273
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia dbAMP 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and dbAMP 3.0, with an available 3D structural model.
Sequence
LPKPPKPVSKMRMATPLLMQALPM
Physicochemical Analysis
C121H211N31O28S4
NDCEGHIFWY
P
2676.44
11.73
4
0
11
+4
3.90
-0.008
85.42
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
4
L
3
K
4
M
0
F
6
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 4 K: 3 M: 4 F: 0 P: 6 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
24
C121H211N31O28S4
2676.44
11.73
+4
3.90
-0.008
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials. | PLoS Negl Trop Dis | 2019
Evidence 2 Activity

Activity

30% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
30% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials. | PLoS Negl Trop Dis | 2019