Back to search

Peptide record

TPDB03267

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB03267
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LFKLLGKIIHHVGNFVHGFSHVF
Physicochemical Analysis
C130H192N34O26
ARDCEQMPTWY
HF
2647.17
10.60
6
0
12
+2
-0.21
0.787
122.61
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
3
G
4
H
2
I
3
L
2
K
0
M
4
F
0
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 4 I: 2 L: 3 K: 2 M: 0 F: 4 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
23
C130H192N34O26
2647.17
10.60
+2
-0.21
0.787
Evidence Records 3 records
Evidence 1 Activity

Activity

24% Cell death
Toxicity
32 µg/mL
Cytotoxic
24% Cell death | 32 | µg/mL | target cell: Human renal proximal tubular epithelial cells (HRPTEC)

Target

Human renal proximal tubular epithelial cells (HRPTEC)

Source & Reference

NA
DBAASP
Chemical "Butterfly Effect" Explaining the Coordination Chemistry and Antimicrobial Properties of Clavanin Complexes. | Inorg Chem | 2021
Evidence 2 Activity

Activity

0% Cell death
Toxicity
256 µg/mL
Cytotoxic
0% Cell death | 256 | µg/mL | target cell: Human renal proximal tubular epithelial cells (HRPTEC)

Target

Human renal proximal tubular epithelial cells (HRPTEC)

Source & Reference

NA
DBAASP
Chemical "Butterfly Effect" Explaining the Coordination Chemistry and Antimicrobial Properties of Clavanin Complexes. | Inorg Chem | 2021
Evidence 3 Activity

Activity

3% Cell death
Toxicity
16 µg/mL
Cytotoxic
3% Cell death | 16 | µg/mL | target cell: Human renal proximal tubular epithelial cells (HRPTEC)

Target

Human renal proximal tubular epithelial cells (HRPTEC)

Source & Reference

NA
DBAASP
Chemical "Butterfly Effect" Explaining the Coordination Chemistry and Antimicrobial Properties of Clavanin Complexes. | Inorg Chem | 2021