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Peptide record

TPDB03252

Antibacterial Antiparasitic Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB03252
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia i2APP PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, i2APP, and other sources, with an available 3D structural model.
Sequence
GIKKFLHIIWKFIKAFVGEIMNS
Physicochemical Analysis
C133H207N31O28S1
RDCQPTY
I
2720.36
10.55
5
1
13
+3
-0.17
0.622
118.70
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
202.18
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
1
E
0
Q
2
G
1
H
5
I
1
L
4
K
1
M
3
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 1 I: 5 L: 1 K: 4 M: 1 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C133H207N31O28S1
2720.36
10.55
+3
-0.17
0.622
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
2.9 µM
Hemolytic Cytotoxic
50% Hemolysis | 2.9 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Position-dependent hydrophobicity of the antimicrobial magainin peptide affects the mode of peptide-lipid interactions and selective toxicity. | Biochemistry | 2002
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis