Back to search

Peptide record

TPDB03240

Antibacterial Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB03240
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GIKKWVKGVAKGVAKDLAKKIL
Physicochemical Analysis
C111H196N30O25
RNCEQHMFPSTY
K
2350.96
10.92
7
1
11
+6
4.30
0.077
124.09
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
233.95
0
Residue Composition
number
3
A
0
R
0
N
1
D
0
C
0
E
0
Q
3
G
0
H
2
I
2
L
7
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 2 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
22
C111H196N30O25
2350.96
10.92
+6
4.30
0.077
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designed peptide with a flexible central motif from ranatuerins adapts its conformation to bacterial membranes. | Biochim Biophys Acta | 2018
Evidence 2 Activity

Activity

50% Cell death
Toxicity
30 µM
Cytotoxic
50% Cell death | 30 | µM | target cell: Human skin fibroblasts

Target

Human skin fibroblasts

Source & Reference

NA
DBAASP
Designed peptide with a flexible central motif from ranatuerins adapts its conformation to bacterial membranes. | Biochim Biophys Acta | 2018