Peptide record

TPDB03230

Antibacterial Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB03230
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
MQTFQDILGKVIEVIKAIVDAK
Physicochemical Analysis
C112H191N27O32S1
RNCHPSWY
I
2459.97
7.02
3
3
12
+0
5.47
0.564
137.27
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
0
N
2
D
0
C
1
E
2
Q
1
G
0
H
4
I
1
L
3
K
1
M
1
F
0
P
0
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 2 C: 0 E: 1 Q: 2 G: 1 H: 0 I: 4 L: 1 K: 3 M: 1 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
22
C112H191N27O32S1
2459.97
7.02
+0
5.47
0.564
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
10% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of amino acid substitution in the staphylococcal peptides warnericin RK and PSM? on their anti-Legionella and hemolytic activities. | Mol Cell Biochem | 2015
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis