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Peptide record

TPDB03228

Antibacterial Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB03228
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
MADVIAKFFEIVKGLIDQFTQK
Physicochemical Analysis
C119H189N27O32S1
RNCHPSWY
IKF
2542.03
7.02
3
3
12
+0
3.45
0.423
106.36
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
0
N
2
D
0
C
1
E
2
Q
1
G
0
H
3
I
1
L
3
K
1
M
3
F
0
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 2 C: 0 E: 1 Q: 2 G: 1 H: 0 I: 3 L: 1 K: 3 M: 1 F: 3 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
22
C119H189N27O32S1
2542.03
7.02
+0
3.45
0.423
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>20 µM
Hemolytic Cytotoxic
10% Hemolysis | >20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of amino acid substitution in the staphylococcal peptides warnericin RK and PSM? on their anti-Legionella and hemolytic activities. | Mol Cell Biochem | 2015
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis