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Peptide record

TPDB03223

Antibacterial Anticancer Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB03223
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
MQFITDLIKKAVDFFKGLFDNK
Physicochemical Analysis
C124H192N28O32S1
RCEHPSWY
KF
2619.12
9.67
4
3
11
+1
2.21
0.068
88.64
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
0
R
1
N
3
D
0
C
0
E
1
Q
1
G
0
H
2
I
2
L
4
K
1
M
4
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 3 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 2 L: 2 K: 4 M: 1 F: 4 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
22
C124H192N28O32S1
2619.12
9.67
+1
2.21
0.068
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
12.36 µM
Hemolytic Cytotoxic
10% Hemolysis | 12.36 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Specific Anti-Leukemic Activity of the Peptide Warnericin RK and Analogues and Visualization of Their Effect on Cancer Cells by Chemical Raman Imaging. | PLoS One | 2016
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes:10% Hemolysis=12.36µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
PLoS One. 2016 Sep 6 11(9):e0162007.
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis