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Peptide record

TPDB03217

BF2 Antibacterial Anticancer Cell-penetrating Peptides Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB03217
BF2
Antibacterial Anticancer Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and CPPsite3.0, with an available 3D structural model.
Sequence
TRSSRAGLQWPVGRVHRLLRK
Physicochemical Analysis
C108H185N41O26
NDCEIMFY
R
2473.92
13.00
7
0
7
+6
3.89
-0.814
88.10
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
5500
222.32
4
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
1
Q
2
G
1
H
0
I
3
L
1
K
0
M
0
F
1
P
2
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 0 L: 3 K: 1 M: 0 F: 0 P: 1 S: 2 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
21
C108H185N41O26
2473.92
13.00
+6
3.89
-0.814
Free
L
Linear
Free
Evidence Records 3 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli Strain Carolina #25922

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Protein derived
Higher arginine content improved translocation for buforin II
In vitro
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Dimerization of cell-penetrating buforin II enhances antimicrobial properties. | J Anal Sci Technol | 2021
Evidence 3 Activity

Activity

3% Hemolysis
Toxicity
810 µM
Hemolytic Cytotoxic
3% Hemolysis | 810 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP