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Peptide record

TPDB03123

FLAK 25 Antibacterial Anticancer Antifungal standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB03123
FLAK 25
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb iACP-DRLF Antifungipept CAFPdb dbAMP
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
VAKKLAKLAKKLAKLALAL-NH2
Physicochemical Analysis
C95H179N25O20
RNDCEQGHIMFPSTWY
ALK
1991.62
11.21
6
0
13
+6
1.63
0.758
170.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C95H179N25O20
1991.62
11.21
+6
1.63
0.758
Amidation
L
Linear
Free
Anticancer
FLAK peptides
Evidence Records 2 records
Evidence 1 Activity

Activity

LD50
LD50 =130 µg/ml
Anticancer
130 µg/mL

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Not Available
Anticancer

Target

Skin Cancer
BMKC
Skin

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2