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Peptide record

TPDB03114

Antibacterial Anticancer Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB03114
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
CVKVSVKVGSGVKVSVKVC
Physicochemical Analysis
C83H153N23O23S2
ARNDEQHILMFPTWY
V
1905.39
10.17
4
0
8
+4
4.45
1.042
122.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
6.56
5
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
2
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
3
S
0
T
0
W
0
Y
8
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 8
Chemical Descriptors
19
C83H153N23O23S2
1905.39
10.17
+4
4.45
1.042
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
589 µM
Hemolytic Cytotoxic
50% Hemolysis | 589 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De novo design of potent antimicrobial peptides | Antimicrob Agents Chemother | 2004
Evidence 2 Activity

Activity

EC50
Toxicity
589000 nM
Hemolytic
Hemolytic_activity: [Ref.15328096]EC50=589000 nM against human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2004 Sep 48(9):3349-3357.