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Peptide record

TPDB03107

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB03107
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RPDKPRPYLPRPRPPRPVR
Physicochemical Analysis
C106H176N38O23
ANCEQGHIMFSTW
P
2350.80
12.41
7
1
3
+6
9.25
-2.132
35.79
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
63.38
1
Residue Composition
number
0
A
6
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
8
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 8 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
19
C106H176N38O23
2350.80
12.41
+6
9.25
-2.132
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-negative bacteria. It also prevents B. anthracis mortality by deactivating bacterial toxins ( Otvos et al., 2014 ).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-negative bacteria. It also prevents B. anthracis mortality by deactivating bacterial toxins ( Otvos et al., 2014 ).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against Gram-negative bacteria. It also prevents B. anthracis mortality by deactivating bacterial toxins ( Otvos et al., 2014 ).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Active against Gram-negative bacteria. It also prevents B. anthracis mortality by deactivating bacterial toxins ( Otvos et al., 2014 ).
Evidence 5 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
C-terminal modifications broaden the activity of the proline-rich antimicrobial peptide, Chex1-Arg20. | Aust J Chem | 2015