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Peptide record

TPDB03032

Antibacterial Anticancer Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB03032
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 pep-lab Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, pep-lab, and Peptipedia, with an available 3D structural model.
Sequence
GIFSKLAGKKLKNLLISG
Physicochemical Analysis
C88H155N23O22
RDCEQHMPTWYV
LK
1887.34
11.00
4
0
8
+4
0.51
0.383
135.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
3
G
0
H
2
I
4
L
4
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 4 K: 4 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C88H155N23O22
1887.34
11.00
+4
0.51
0.383
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
10% Hemolysis | 64 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Frog Skin-Derived Peptides Against Corynebacterium jeikeium: Correlation between Antibacterial and Cytotoxic Activities | Antibiotics (Basel) | 2020
Evidence 2 Activity

Activity

20% Killing
Toxicity
64 µM
Cytotoxic
20% Killing | 64 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Frog Skin-Derived Peptides Against Corynebacterium jeikeium: Correlation between Antibacterial and Cytotoxic Activities | Antibiotics (Basel) | 2020
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Sheep erythrocytes: 10% Hemolysis=64 µM | Cytotoxicity: HaCat: 20% Killing=64 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Antibiotics (Basel). 2020 Jul 26 9(8):448.