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Peptide record

TPDB03028

Antibacterial Antiparasitic Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB03028
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia dbAMP 3.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
GILNTIKSIASKLKRKAK
Physicochemical Analysis
C88H165N27O23
DCEQHMFPWYV
K
1969.45
11.85
6
0
7
+6
4.20
-0.306
119.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
2
A
1
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
5
K
0
M
0
F
0
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 5 M: 0 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C88H165N27O23
1969.45
11.85
+6
4.20
-0.306
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
640 µM
Hemolytic Cytotoxic
50% Hemolysis | 640 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin. | Biochim Biophys Acta | 2013
Evidence 2 Activity

Activity

50% Cell death
Toxicity
139 µM
Cytotoxic
50% Cell death | 139 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin. | Biochim Biophys Acta | 2013
Evidence 3 Activity

Activity

50% Cell death
Toxicity
123 µM
Cytotoxic
50% Cell death | 123 | µM | target cell: Human COS-7 cells

Target

Human COS-7 cells

Source & Reference

NA
DBAASP
Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin. | Biochim Biophys Acta | 2013
Evidence 4 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis