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Peptide record

TPDB03010

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB03010
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GGLRSLGLKILLAWKKYG
Physicochemical Analysis
C94H157N25O21
NDCEQHMFPTV
L
1973.44
10.91
4
0
9
+4
-2.12
0.250
135.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
354.20
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
1
I
5
L
3
K
0
M
0
F
0
P
1
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 5 K: 3 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
18
C94H157N25O21
1973.44
10.91
+4
-2.12
0.250
Evidence Records 2 records
Evidence 1 Activity

Activity

0.27±0.44% Hemolysis
Toxicity
6.25 µM
Hemolytic Cytotoxic
0.27±0.44% Hemolysis | 6.25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A QSAR modeling approach for predicting myeloid antimicrobial peptides with high sequence similarity. | Chem Biol Drug Des | 2020
Evidence 2 Activity

Activity

14.9±2.5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
14.9±2.5% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A QSAR modeling approach for predicting myeloid antimicrobial peptides with high sequence similarity. | Chem Biol Drug Des | 2020