Peptide record

TPDB03008

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB03008
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKLFKKILKYLKFLHSAK
Physicochemical Analysis
C111H185N27O21
RNDCEQGMPTWV
K
2233.86
10.95
8
0
9
+7
2.10
-0.306
113.89
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
66.70
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
4
L
7
K
0
M
2
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 4 K: 7 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
18
C111H185N27O21
2233.86
10.95
+7
2.10
-0.306
Evidence Records 3 records
Evidence 1 Activity

Activity

12% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
12% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 2 Activity

Activity

54% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
54% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 3 Activity

Activity

58% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
58% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013