Peptide record

TPDB03001

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB03001
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GGLRRLGRKILRAVKKYG
Physicochemical Analysis
C91H165N33O20
NDCEQHMFPSTW
RG
2041.52
12.42
7
0
7
+7
3.22
-0.594
108.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
72.98
1
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
1
I
3
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 3 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
18
C91H165N33O20
2041.52
12.42
+7
3.22
-0.594
Evidence Records 1 records
Evidence 1 Activity

Activity

0.2±0.2% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0.2±0.2% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A QSAR modeling approach for predicting myeloid antimicrobial peptides with high sequence similarity. | Chem Biol Drug Des | 2020