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Peptide record

TPDB02995

Antibacterial Antifungal standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB02995
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
WKLLSKAQEKFGKNKSR
Physicochemical Analysis
C93H154N28O24
DCHIMPTYV
K
2048.42
11.10
6
1
5
+5
4.78
-1.482
51.76
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
268.50
4
Residue Composition
number
1
A
1
R
1
N
0
D
0
C
1
E
1
Q
1
G
0
H
0
I
2
L
5
K
0
M
1
F
0
P
2
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 0 I: 0 L: 2 K: 5 M: 0 F: 1 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C93H154N28O24
2048.42
11.10
+5
4.78
-1.482
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
7 µM

Target

Pseudomonas aeruginosa Pak

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram- E. coli O157:H7 or K12 (MIC 5.8-25 uM), P. aeruginosa Pak (MIC 7 uM), A.naeslundii (MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µM

Target

A.naeslundii

Source & Reference

dbAMP

Other

ctive against Gram- E. coli O157:H7 or K12 (MIC 5.8-25 uM), P. aeruginosa Pak (MIC 7 uM), A.naeslundii (MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µM

Target

P.gingivalis HG 66

Source & Reference

dbAMP

Other

O157:H7 or K12 (MIC 5.8-25 uM), P. aeruginosa Pak (MIC 7 uM), A.naeslundii (MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100
Evidence 4 Activity

Activity

MIC
Antibacterial
18 µM

Target

B. subtilis ATCC 9372

Source & Reference

dbAMP

Other

ginosa Pak (MIC 7 uM), A.naeslundii (MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100 uM), and yeast C. albicans ATCC 10231 (M
Evidence 5 Activity

Activity

MIC
Antibacterial
>100 µM

Target

S.sanguis SK4

Source & Reference

dbAMP

Other

(MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100 uM), and yeast C. albicans ATCC 10231 (MIC 2.1 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µM

Target

S.mutans

Source & Reference

dbAMP

Other

HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100 uM), and yeast C. albicans ATCC 10231 (MIC 2.1 uM).
Evidence 7 Activity

Activity

MIC
Antibacterial
2.1 µM

Target

Candida albicans ATCC 10231

Source & Reference

dbAMP

Other

lis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100 uM), and yeast C. albicans ATCC 10231 (MIC 2.1 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
7 µM

Target

Pseudomonas aeruginosa Pak

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram- E. coli O157:H7 or K12 (MIC 5.8-25 uM), P. aeruginosa Pak (MIC 7 uM), A.naeslundii (MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372
Evidence 9 Activity

Activity

MIC
Antifungal
>100 µM

Target

A.naeslundii

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ctive against Gram- E. coli O157:H7 or K12 (MIC 5.8-25 uM), P. aeruginosa Pak (MIC 7 uM), A.naeslundii (MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4
Evidence 10 Activity

Activity

MIC
Antifungal
>100 µM

Target

P.gingivalis HG 66

Source & Reference

dbAMP CAFPdb Antifungipept

Other

O157:H7 or K12 (MIC 5.8-25 uM), P. aeruginosa Pak (MIC 7 uM), A.naeslundii (MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100
Evidence 11 Activity

Activity

MIC
Antifungal
18 µM

Target

B. subtilis ATCC 9372

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ginosa Pak (MIC 7 uM), A.naeslundii (MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100 uM), and yeast C. albicans ATCC 10231 (M
Evidence 12 Activity

Activity

MIC
Antifungal
>100 µM

Target

S.sanguis SK4

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC >100 uM), P.gingivalis HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100 uM), and yeast C. albicans ATCC 10231 (MIC 2.1 uM).
Evidence 13 Activity

Activity

MIC
Antifungal
>100 µM

Target

S.mutans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

HG 66 (MIC>100 uM), Gram+ B. subtilis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100 uM), and yeast C. albicans ATCC 10231 (MIC 2.1 uM).
Evidence 14 Activity

Activity

MIC
Antifungal
2.1 µM

Target

Candida albicans ATCC 10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

lis ATCC 9372 (MIC 18 uM), S.sanguis SK4 (MIC >100 uM), S.mutans (MIC >100 uM), and yeast C. albicans ATCC 10231 (MIC 2.1 uM).