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Peptide record

TPDB02988

Antibacterial Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB02988
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KKKKKKAAFLAWALFAA
Physicochemical Analysis
C95H154N24O18
RNDCEQGHIMPSTYV
AK
1920.42
11.21
6
0
11
+6
-0.31
-0.018
81.18
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
286.40
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
6
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 6 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C95H154N24O18
1920.42
11.21
+6
-0.31
-0.018
Evidence Records 5 records
Evidence 1 Activity

Activity

24% Hemolysis
Toxicity
650 µM
Hemolytic Cytotoxic
24% Hemolysis | 650 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membrane interactions of designed cationic antimicrobial peptides: the two thresholds. | Biopolymers | 2008
Evidence 2 Activity

Activity

16% Hemolysis
Toxicity
325 µM
Hemolytic Cytotoxic
16% Hemolysis | 325 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membrane interactions of designed cationic antimicrobial peptides: the two thresholds. | Biopolymers | 2008
Evidence 3 Activity

Activity

10% Hemolysis
Toxicity
162 µM
Hemolytic Cytotoxic
10% Hemolysis | 162 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membrane interactions of designed cationic antimicrobial peptides: the two thresholds. | Biopolymers | 2008
Evidence 4 Activity

Activity

11% Hemolysis
Toxicity
81 µM
Hemolytic Cytotoxic
11% Hemolysis | 81 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membrane interactions of designed cationic antimicrobial peptides: the two thresholds. | Biopolymers | 2008
Evidence 5 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis