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Peptide record

TPDB02915

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB02915
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RGGRLCYCRRRFCVCE
Physicochemical Analysis
C80H133N31O20S4
ANDQHIKMPSTW
R
1977.37
9.27
5
1
4
+4
2.57
-0.456
42.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1740
88.00
5
Residue Composition
number
0
A
5
R
0
N
0
D
4
C
1
E
0
Q
2
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 4 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
16
C80H133N31O20S4
1977.37
9.27
+4
2.57
-0.456
Evidence Records 2 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 80 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006
Evidence 2 Activity

Activity

50% Cell death
Toxicity
100-200 µg/mL
Cytotoxic
50% Cell death | 100-200 | µg/mL | target cell: Human epithelial cells

Target

Human epithelial cells

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006