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Peptide record

TPDB02908

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB02908
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
TLSKEKERIVQRVRTS
Physicochemical Analysis
C81H148N28O26
ANDCGHMFPWY
R
1930.24
11.37
5
2
4
+3
8.84
-1.131
85.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
2
E
1
Q
0
G
0
H
1
I
1
L
2
K
0
M
0
F
0
P
2
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 2 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 2 M: 0 F: 0 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
16
C81H148N28O26
1930.24
11.37
+3
8.84
-1.131
Evidence Records 3 records
Evidence 1 Activity

Activity

>0.5% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
>0.5% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The activity and action mechanism of novel short selective LL-37-derived anticancer peptides against clinical isolates of Escherichia coli. | Chem Biol Drug Des | 2019
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
The activity and action mechanism of novel short selective LL-37-derived anticancer peptides against clinical isolates of Escherichia coli. | Chem Biol Drug Des | 2019
Evidence 3 Activity

Activity

15% Cytotoxicity
Toxicity
50 µg/mL
Cytotoxic
15% Cytotoxicity | 50 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
The activity and action mechanism of novel short selective LL-37-derived anticancer peptides against clinical isolates of Escherichia coli. | Chem Biol Drug Des | 2019