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Peptide record

TPDB02906

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB02906
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RPAWRKAAFRVMRACV
Physicochemical Analysis
C85H140N30O17S2
NDEQGHILSTY
AR
1918.36
12.41
5
0
9
+5
0.69
-0.100
61.25
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
286.70
1
Residue Composition
number
4
A
4
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
1
M
1
F
1
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 4 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 1 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
16
C85H140N30O17S2
1918.36
12.41
+5
0.69
-0.100
Evidence Records 2 records
Evidence 1 Activity

Activity

4% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 80 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Origin of low mammalian cell toxicity in a class of highly active antimicrobial amphipathic helical peptides. | J Biol Chem | 2008
Evidence 2 Activity

Activity

21% Hemolysis
Toxicity
2500 µg/mL
Hemolytic Cytotoxic
21% Hemolysis | 2500 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Origin of low mammalian cell toxicity in a class of highly active antimicrobial amphipathic helical peptides. | J Biol Chem | 2008