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Peptide record

TPDB02905

Antibacterial Hemolysis Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB02905
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
RPAWLKAAFRVMRACV
Physicochemical Analysis
C85H139N27O17S2
NDEQGHISTY
A
1875.33
12.12
4
0
10
+4
-0.68
0.419
85.62
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
293.28
1
Residue Composition
number
4
A
3
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
1
M
1
F
1
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 3 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 1 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
16
C85H139N27O17S2
1875.33
12.12
+4
-0.68
0.419
Evidence Records 3 records
Evidence 1 Activity

Activity

80% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
80% Hemolysis | 80 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Origin of low mammalian cell toxicity in a class of highly active antimicrobial amphipathic helical peptides. | J Biol Chem | 2008
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
2500 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 2500 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Origin of low mammalian cell toxicity in a class of highly active antimicrobial amphipathic helical peptides. | J Biol Chem | 2008
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis