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Peptide record

TPDB02848

Antibacterial Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB02848
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
VCYCRRRFCVCVGR
Physicochemical Analysis
C71H118N26O16S4
ANDEQHILKMPSTW
RC
1720.12
9.27
4
0
5
+4
0.43
0.407
62.14
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1740
101.16
5
Residue Composition
number
0
A
4
R
0
N
0
D
4
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 3
Chemical Descriptors
14
C71H118N26O16S4
1720.12
9.27
+4
0.43
0.407
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 80 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006
Evidence 2 Activity

Activity

50% Cell death
Toxicity
25-50 µg/mL
Cytotoxic
50% Cell death | 25-50 | µg/mL | target cell: Human epithelial cells

Target

Human epithelial cells

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis