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Peptide record

TPDB02847

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB02847
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ECYCRRRFCVCVGR
Physicochemical Analysis
C71H116N26O18S4
ANDQHILKMPSTW
RC
1750.11
8.73
4
1
4
+3
2.38
-0.143
41.43
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
1740
99.42
5
Residue Composition
number
0
A
4
R
0
N
0
D
4
C
1
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 4 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
14
C71H116N26O18S4
1750.11
8.73
+3
2.38
-0.143
Evidence Records 2 records
Evidence 1 Activity

Activity

6% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
6% Hemolysis | 80 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006
Evidence 2 Activity

Activity

50% Cell death
Toxicity
50-100 µg/mL
Cytotoxic
50% Cell death | 50-100 | µg/mL | target cell: Human epithelial cells

Target

Human epithelial cells

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006