Back to search

Peptide record

TPDB02840

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB02840
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
WIRRIKKWIRRVHK
Physicochemical Analysis
C93H155N33O15
ANDCEQGLMFPSTY
R
1975.47
12.88
8
0
6
+7
2.61
-1.214
104.29
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
556.83
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
3
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 3 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
14
C93H155N33O15
1975.47
12.88
+7
2.61
-1.214
Evidence Records 3 records
Evidence 1 Activity

Activity

EC50
Toxicity
128 µM
Cytotoxic
EC50 | 128 | µM | target cell: Murine macrophage cells J774A.1

Target

Murine macrophage cells J774A.1

Source & Reference

NA
DBAASP
A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. | Sci Rep | 2017
Evidence 2 Activity

Activity

EC50
Toxicity
64 µM
Cytotoxic
EC50 | 64 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. | Sci Rep | 2017
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
50% Hemolysis | 256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. | Sci Rep | 2017