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Peptide record

TPDB02795

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB02795
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
ILPWKWPFFPWRR
Physicochemical Analysis
C96H129N23O14
ANDCEQGHMSTYV
PW
1829.23
12.41
3
0
7
+3
-4.72
-0.500
60.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
16500
902.02
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
2
F
3
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 2 P: 3 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
13
C96H129N23O14
1829.23
12.41
+3
-4.72
-0.500
Evidence Records 2 records
Evidence 1 Activity

Activity

21% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
21% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Coupling molecular dynamics simulations with experiments for the rational design of indolicidin-analogous antimicrobial peptides. | J Mol Biol | 2009
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis