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Peptide record

TPDB02705

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB02705
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
MKKALQYIKLLKE
Physicochemical Analysis
C75H132N18O18S1
RNDCGHFPSTWV
K
1606.04
10.31
4
1
7
+3
3.23
-0.331
127.69
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
92.77
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
1
I
3
L
4
K
1
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 1 L: 3 K: 4 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
13
C75H132N18O18S1
1606.04
10.31
+3
3.23
-0.331
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
<5% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Shorter Antibacterial Peptide Having High Selectivity for E. coli Membranes and Low Potential for Inducing Resistance. | Microorganisms | 2020