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Peptide record

TPDB02630

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB02630
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKMKKALQYIKL
Physicochemical Analysis
C70H126N18O15S1
RNDCEGHFPSTWV
K
1491.94
10.77
5
0
6
+5
2.76
-0.708
105.83
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
99.87
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
2
L
5
K
1
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 2 K: 5 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C70H126N18O15S1
1491.94
10.77
+5
2.76
-0.708
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<5% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Shorter Antibacterial Peptide Having High Selectivity for E. coli Membranes and Low Potential for Inducing Resistance. | Microorganisms | 2020