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Peptide record

TPDB02623

Antibacterial Hemolysis Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB02623
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
LCYCRRRFCVC
Physicochemical Analysis
C59H96N20O13S4
ANDEQGHIKMPSTW
C
1421.78
8.73
3
0
4
+3
-1.09
0.545
61.82
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1740
122.38
5
Residue Composition
number
0
A
3
R
0
N
0
D
4
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
11
C59H96N20O13S4
1421.78
8.73
+3
-1.09
0.545
Evidence Records 3 records
Evidence 1 Activity

Activity

12% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
12% Hemolysis | 80 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006
Evidence 2 Activity

Activity

50% Cell death
Toxicity
50-100 µg/mL
Cytotoxic
50% Cell death | 50-100 | µg/mL | target cell: Human epithelial cells

Target

Human epithelial cells

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis