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Peptide record

TPDB02614

Antibacterial Antifungal Hemolysis Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB02614
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
WKLFKKILKFL
Physicochemical Analysis
C77H122N16O12
ARNDCEQGHMPSTYV
K
1463.92
11.00
4
0
7
+4
-2.14
0.455
141.82
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
375.70
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
4
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
11
C77H122N16O12
1463.92
11.00
+4
-2.14
0.455
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
50% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inhibition of plant-pathogenic bacteria by short synthetic cecropin A-melittin hybrid peptides. | Appl Environ Microbiol | 2006
Evidence 2 Activity

Activity

95% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
95% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples. | Appl Environ Microbiol | 2009
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis