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Peptide record

TPDB02612

Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB02612
Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP CellPPD-MOD CPPsite3.0 PerseuCPP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KKLFKKILKKL
Physicochemical Analysis
C69H127N17O12
ARNDCEQGHMPSTWYV
K
1386.87
11.21
6
0
5
+6
2.82
-0.427
141.82
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
6
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 6 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C69H127N17O12
1386.87
11.21
+6
2.82
-0.427
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5-5.0 µM

Target

v. syringae

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against plant pathogenic bacterial strains P. syringae pv. syringae (MIC 2.5-5.0 uM), X. axonopodis pv. vesicatoria (MIC 2.5-5.0 uM), and E-amylovora (MIC >7.5 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
2.5-5.0 µM

Target

v. vesicatoria

Source & Reference

dbAMP

Other

nt pathogenic bacterial strains P. syringae pv. syringae (MIC 2.5-5.0 uM), X. axonopodis pv. vesicatoria (MIC 2.5-5.0 uM), and E-amylovora (MIC >7.5 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
2.5-5.0 µM

Target

v. syringae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against plant pathogenic bacterial strains P. syringae pv. syringae (MIC 2.5-5.0 uM), X. axonopodis pv. vesicatoria (MIC 2.5-5.0 uM), and E-amylovora (MIC >7.5 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
2.5-5.0 µM

Target

v. vesicatoria

Source & Reference

dbAMP CAFPdb Antifungipept

Other

nt pathogenic bacterial strains P. syringae pv. syringae (MIC 2.5-5.0 uM), X. axonopodis pv. vesicatoria (MIC 2.5-5.0 uM), and E-amylovora (MIC >7.5 uM).
Evidence 5 Activity

Activity

8% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
8% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A library of linear undecapeptides with bactericidal activity against phytopathogenic bacteria. | Peptides | 2007
Evidence 6 Activity

Activity

14% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
14% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A library of linear undecapeptides with bactericidal activity against phytopathogenic bacteria. | Peptides | 2007
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
0% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 8 Activity

Activity

IC50
Toxicity
>200 µM
Cytotoxic
IC50 | >200 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties. | Org Biomol Chem | 2014