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Peptide record

TPDB02595

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02595
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
PFFWRIRIRR
Physicochemical Analysis
C70H107N23O11
ANDCEQGHLKMSTYV
R
1446.77
12.88
4
0
5
+4
-1.04
-0.590
78.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
380.16
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
2
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 2 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
10
C70H107N23O11
1446.77
12.88
+4
-1.04
-0.590
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides. | J Biol Chem | 2011