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Peptide record

TPDB02593

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02593
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
CYCRRRFCVC
Physicochemical Analysis
C53H85N19O12S4
ANDEQGHILKMPSTW
C
1308.62
8.73
3
0
3
+3
-0.53
0.220
29.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1740
132.96
5
Residue Composition
number
0
A
3
R
0
N
0
D
4
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
10
C53H85N19O12S4
1308.62
8.73
+3
-0.53
0.220
Evidence Records 2 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 80 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006
Evidence 2 Activity

Activity

50% Cell death
Toxicity
200-400 µg/mL
Cytotoxic
50% Cell death | 200-400 | µg/mL | target cell: Human epithelial cells

Target

Human epithelial cells

Source & Reference

NA
DBAASP
Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions | Biochim Biophys Acta | 2006