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Peptide record

TPDB02591

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02591
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FWQRNIRKWR
Physicochemical Analysis
C70H104N24O13
ADCEGHLMPSTYV
R
1489.75
12.71
4
0
4
+4
-0.72
-1.890
39.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
738.38
2
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
10
C70H104N24O13
1489.75
12.71
+4
-0.72
-1.890
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides. | J Biol Chem | 2011
Evidence 2 Activity

Activity

42% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
42% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Studies on lactoferricin-derived Escherichia coli membrane-active peptides reveal differences in the mechanism of N-acylated versus nonacylated peptides. | J Biol Chem | 2011