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Peptide record

TPDB02585

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02585
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GVVKRIKTVV
Physicochemical Analysis
C50H95N15O12
ANDCEQHLMFPSWY
V
1098.40
11.64
3
0
5
+3
2.91
0.790
155.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
10
C50H95N15O12
1098.40
11.64
+3
2.91
0.790
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>500 µM
Hemolytic Cytotoxic
50% Hemolysis | >500 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design of alpha-helical antimicrobial peptides: do's and don'ts. | Chembiochem | 2015