Back to search

Peptide record

TPDB02578

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB02578
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RGRKGGRRKK
Physicochemical Analysis
C48H95N25O11
ANDCEQHILMFPSTWYV
R
1198.44
12.88
7
0
0
+7
6.24
-3.090
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C48H95N25O11
1198.44
12.88
+7
6.24
-3.090
Evidence Records 7 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>10000 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >10000 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. | J Med Chem | 2015
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
8602±1269 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 8602±1269 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. | J Med Chem | 2015
Evidence 3 Activity

Activity

10% Hemolysis
Toxicity
6670±29 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 6670±29 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. | J Med Chem | 2015
Evidence 4 Activity

Activity

10% Hemolysis
Toxicity
5064±37 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 5064±37 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. | J Med Chem | 2015
Evidence 5 Activity

Activity

10% Hemolysis
Toxicity
517±66 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 517±66 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. | J Med Chem | 2015
Evidence 6 Activity

Activity

10% Hemolysis
Toxicity
82±5 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 82±5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. | J Med Chem | 2015
Evidence 7 Activity

Activity

10% Hemolysis
Toxicity
64±5 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 64±5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. | J Med Chem | 2015