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Peptide record

TPDB02576

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02576
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FCIRLATYVI
Physicochemical Analysis
C57H91N13O13S1
NDEQGHKMPSW
I
1198.49
8.91
1
0
7
+1
-2.64
1.760
156.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
124.32
3
Residue Composition
number
1
A
1
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
0
M
1
F
0
P
0
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
10
C57H91N13O13S1
1198.49
8.91
+1
-2.64
1.760
Evidence Records 1 records
Evidence 1 Activity

Activity

6% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
6% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of New Delhi metallo-beta-lactamase-1 inhibitor peptides that potentiate meropenem-dependent killing of carbapenemase-producing Enterobacteriaceae. | J Antimicrob Chemother | 2020