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Peptide record

TPDB02570

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02570
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
IKLLCRVHKK
Physicochemical Analysis
C56H104N18O11S1
ANDEQGMFPSTWY
K
1237.62
10.83
5
0
4
+4
3.14
-0.060
146.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
1
C
0
E
0
Q
0
G
1
H
1
I
2
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 2 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C56H104N18O11S1
1237.62
10.83
+4
3.14
-0.060
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
<640 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | <640 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
A short peptide with selective antibiofilm activity against Pseudomonas aeruginosa and Klebsiella pneumoniae carbapenemase-producing bacteria. | Microb Pathog | 2019
Evidence 2 Activity

Activity

IC50
Toxicity
320 µg/mL
Cytotoxic
IC50 | 320 | µg/mL | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
A short peptide with selective antibiofilm activity against Pseudomonas aeruginosa and Klebsiella pneumoniae carbapenemase-producing bacteria. | Microb Pathog | 2019