Back to search

Peptide record

TPDB02555

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB02555
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
YNYSYIITRS
Physicochemical Analysis
C59H86N14O18
ADCEQGHLKMFPWV
Y
1279.41
9.48
1
0
5
+1
-1.81
-0.520
78.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
4470
349.38
7
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
0
F
0
P
2
S
1
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 3 V: 0
Chemical Descriptors
10
C59H86N14O18
1279.41
9.48
+1
-1.81
-0.520
Evidence Records 1 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
2% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of New Delhi metallo-beta-lactamase-1 inhibitor peptides that potentiate meropenem-dependent killing of carbapenemase-producing Enterobacteriaceae. | J Antimicrob Chemother | 2020