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Peptide record

TPDB02554

Antibacterial Anticancer Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02554
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LKKLKFKKLQ
Physicochemical Analysis
C62H112N16O12
ARNDCEGHIMPSTWYV
K
1273.67
11.12
5
0
4
+5
2.72
-0.880
117.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C62H112N16O12
1273.67
11.12
+5
2.72
-0.880
Evidence Records 2 records
Evidence 1 Activity

Activity

7% Hemolysis
Toxicity
375 µM
Hemolytic Cytotoxic
7% Hemolysis | 375 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial cyclic decapeptides with anticancer activity | Peptides | 2010
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
0.7 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 7 ± 0.7% Hemolysis=375 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2010 Nov 31(11):2017-26