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Peptide record

TPDB02550

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02550
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
AFRPIPTHSC
Physicochemical Analysis
C50H77N15O13S1
NDEQGLKMWYV
P
1128.31
9.01
2
0
3
+1
1.09
-0.080
49.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
1
R
0
N
0
D
1
C
0
E
0
Q
0
G
1
H
1
I
0
L
0
K
0
M
1
F
2
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 0 K: 0 M: 0 F: 1 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C50H77N15O13S1
1128.31
9.01
+1
1.09
-0.080
Evidence Records 1 records
Evidence 1 Activity

Activity

4% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
4% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of New Delhi metallo-beta-lactamase-1 inhibitor peptides that potentiate meropenem-dependent killing of carbapenemase-producing Enterobacteriaceae. | J Antimicrob Chemother | 2020