Back to search

Peptide record

TPDB02547

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB02547
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ASVTWLLYAM
Physicochemical Analysis
C55H83N11O14S1
RNDCEQGHIKFP
AL
1154.39
5.94
0
0
8
-0
-4.14
1.360
127.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
6990
605.51
3
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
0
K
1
M
0
F
0
P
1
S
1
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 0 M: 1 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 1 V: 1
Chemical Descriptors
10
C55H83N11O14S1
1154.39
5.94
-0
-4.14
1.360
Evidence Records 1 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
3% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of New Delhi metallo-beta-lactamase-1 inhibitor peptides that potentiate meropenem-dependent killing of carbapenemase-producing Enterobacteriaceae. | J Antimicrob Chemother | 2020