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Peptide record

TPDB02538

Antibacterial Hemolysis Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02538
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
PTTVHIIYRI
Physicochemical Analysis
C57H93N15O14
ANDCEQGLKMFSW
I
1212.46
9.88
2
0
5
+1
0.70
0.570
146.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1490
122.89
3
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
3
I
0
L
0
K
0
M
0
F
1
P
0
S
2
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 3 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 2 W: 0 Y: 1 V: 1
Chemical Descriptors
10
C57H93N15O14
1212.46
9.88
+1
0.70
0.570
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
10% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery and characterization of New Delhi metallo-beta-lactamase-1 inhibitor peptides that potentiate meropenem-dependent killing of carbapenemase-producing Enterobacteriaceae. | J Antimicrob Chemother | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis