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Peptide record

TPDB02524

Antibacterial Antifungal Antiviral Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02524
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
AKVTMTCSAS
Physicochemical Analysis
C39H71N11O15S2
RNDEQGHILFPWY
AST
998.18
8.97
1
0
4
+1
0.79
0.530
49.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
2
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
1
M
0
F
0
P
2
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 1 F: 0 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C39H71N11O15S2
998.18
8.97
+1
0.79
0.530
Evidence Records 6 records
Evidence 1 Activity

Activity

90% Cytotoxicity
Toxicity
2943 µg/mL
Cytotoxic
90% Cytotoxicity | 2943 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Antiviral Activity of Synthetic Peptides Derived from Physiological Proteins. | Intervirology | 2018
Evidence 2 Activity

Activity

<2% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
<2% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
In Vitro and In Vivo Anti- Candida Activity and Structural Analysis of Killer Peptide (KP)-Derivatives. | J Fungi (Basel) | 2021
Evidence 3 Activity

Activity

6.41% Killing
Toxicity
10 µM
Cytotoxic
6.41% Killing | 10 | µM | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
In Vitro and In Vivo Anti- Candida Activity and Structural Analysis of Killer Peptide (KP)-Derivatives. | J Fungi (Basel) | 2021
Evidence 4 Activity

Activity

11.8% Killing
Toxicity
25 µM
Cytotoxic
11.8% Killing | 25 | µM | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
In Vitro and In Vivo Anti- Candida Activity and Structural Analysis of Killer Peptide (KP)-Derivatives. | J Fungi (Basel) | 2021
Evidence 5 Activity

Activity

10.29% Killing
Toxicity
50 µM
Cytotoxic
10.29% Killing | 50 | µM | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
In Vitro and In Vivo Anti- Candida Activity and Structural Analysis of Killer Peptide (KP)-Derivatives. | J Fungi (Basel) | 2021
Evidence 6 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.30654366]<10% cytotoxicity against Vero cells at the concentration of 100µg/ mL.

Source & Reference

NA
DRAMP
Intervirology. 2018 61(4):166-173.