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Peptide record

TPDB02512

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB02512
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RYRRKKKMKK
Physicochemical Analysis
C62H116N24O12S1
ANDCEQGHILFPSTWV
K
1421.82
12.17
8
0
2
+8
6.21
-3.240
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
104.80
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
5
K
1
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 5 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
10
C62H116N24O12S1
1421.82
12.17
+8
6.21
-3.240
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
<5% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Shorter Antibacterial Peptide Having High Selectivity for E. coli Membranes and Low Potential for Inducing Resistance. | Microorganisms | 2020